Home - Products - GPCR/G Protein - Endothelin Receptor - Atrial Natriuretic Peptide (ANP) (1-28), rat

Atrial Natriuretic Peptide (ANP) (1-28), rat

CAS No. 88898-17-3

Atrial Natriuretic Peptide (ANP) (1-28), rat( Atrial natriuretic factor (1-28) (rat) )

Catalog No. M29920 CAS No. 88898-17-3

Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 729 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock

Biological Information

  • Product Name
    Atrial Natriuretic Peptide (ANP) (1-28), rat
  • Note
    Research use only, not for human use.
  • Brief Description
    Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.
  • Description
    Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.(In Vitro):Rat ANP (1-28) and rat BNP-45, which are the respective major circulating forms of ANP and BNP in rats, potently inhibited Ang II-stimulated endothelin-1 secretion in a concentration-dependent manner. Rat ANP (5-25) is less effective that Rat ANP(1-28) with respect to inhibiting immunoreactive (ir)-endothelin-1 secretion and increasing cellular cyclic GMP. Rat ANP (1-28) inhibits the secretion of ir-endothelin-1 in a concentration-dependent manner between 0.01 and 1 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Atrial natriuretic factor (1-28) (rat)
  • Pathway
    GPCR/G Protein
  • Target
    Endothelin Receptor
  • Recptor
    Endothelin-1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    88898-17-3
  • Formula Weight
    3062.41
  • Molecular Formula
    C128H205N45O39S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    Sequence:Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr (Disulfide bridge: Cys7-Cys23)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Kohno M, et al. Angiotensin II stimulates endothelin-1 secretion in cultured rat mesangial cells. Kidney Int. 1992 Oct;42(4):860-6.
molnova catalog
related products
  • BMS 182874

    BMS 182874 is an orally effective and highly selective endothelin receptor ETA antagonist with an IC50 value of 0.150 μM for ETA and a Ki value of 0.055 μM for ETA.

  • Enrasentan

    Enrasentan (sb-217242) is a mixed antagonist of ET(A) and ET(B) receptors that reduces blood pressure, prevents cardiac hypertrophy, and protects myocardial function.

  • Edonentan

    Edonentan is A potent endothelin A (ETA) receptor antagonist that can be used to study heart failure.